Your healthcare provider should be able to test testosterone levels and evaluate this with you. Viagra can lose its efficacy over time, due to changes in your body or changes in your health. If that happens, Spar said, you can try switching to another medication in the same class meaning, another PDE5 inhibitor. A doctor can help you decide if another PDE5 is worth trying. In addition to Viagra, the other oral medications that are considered the first-line treatment for ED, according to a review, include:.
A reason that this PDE5 inhibitor is preferred by many people, including healthcare providers treating ED, is that tadalafil has a longer window of activity, meaning you can take it in a daily dose.
This can remove some of the psychological aspects and uncertainty of timing a pill before sex. Plus, it can help to see how effective PDE5 inhibitors are for you. This can be a sign of general atherosclerosis or plaque in the arterial system, Spar said, which is a risk factor for heart attack and stroke.
People with atherosclerotic heart disease have arteries that are plugged with cholesterol plaques or have lost their elasticity, said Ramin. If you have leaky valves, Ramin said, the blood may flow at an increased rate to your penis, but it will all leak out and not stay long enough to cause an erection.
Spar said another reason Viagra does not work for everyone has to do with anxiety and emotional health. This can make it difficult to get sexually excited from a neurotransmitter perspective.
The good news is that some of the things that can have the biggest positive impact on ED symptoms involve actions you can take without a prescription. Some common factors that can lead to conditions affecting blood circulation include:. To help improve your overall health and improve ED symptoms such as circulation, consider these changes:. Of the guys that accepted, 77 percent then responded favorably to the ED drugs. See how men commonly misuse ED drugs, and learn from their mistakes.
When you get sexually excited, your brain sends a signal via the nerves down to your penis. This releases a chemical into the muscle of the penis, which then sparks the production of another chemical—the one your ED meds work on to give you a boner.
It might be tempting to start at the lowest dose—who wants to take more medication than they need? And that can leave guys frustrated. Exception: If you have other health conditions, like hypertension, diabetes, or high cholesterol, your doctor will probably start you on a lower dose to make sure you can tolerate the medication, he says.
Otherwise, ask your doc if your prescription is for the max. Over 20 percent of men in the study made the mistake of taking Viagra or Levitra too soon after eating. Selectivity is the ability of the drug to attach to the specific enzyme PDE 5 found in penile tissues. Vardenafil Levitra is more selective than sildenafil and tadalafil Cialis to PDE5, which again means a lower dose is needed with potentially less side effects. Pharmacokinetics, half-life, is how long the medication stay s in the blood.
Sildenafil Viagra has a half-life of 4 hours and vardenafil Levitra has a half-life of hours while tadalafil Cialis has a half-life of This means that vardenafil Levitra should act longer than sildenafil Viagra but the clinical significance is not known.
Tadalafil Cialis has the longest half-life and allows you to take the medication and not relate the sexual activity to the immediate use of the medication. The drawback is if you need nitrates after using tadalafil Cialis , this medication lasts a long time in your blood stream and may place you at a higher risk.
Younger people might do well treated with tadalafil, Cialis while older people with other health issues might be better off using sildenafil Viagra or vardenafil Levitra but more data are needed. The side effects of vardenafil Levitra are potentially less than sildenafil Viagra , but more data are needed.
In a recent study on men with erectile dysfunction and diabetes, vardenafil Levitra improved their erectile dysfunction. Tadalafil Cialis is as effective as sildenafil Viagra , and vardenafil Levitra with similar side effects except for back pain that occurs occasionally with tadalafil, probably because of the long half-life.
Many people stop taking drugs because they are experiencing side effects, they no longer have a partner, or they are worried about safety. Sexual activity is not a major contributor to the risk of a heart attack.
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